Anti-COL9A1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P20849
Gene Id	1297
Gene Symbols	COL9A1
Protein Name / Synonyms	COL9A1 (Center)
Clonality	Polyclonal
Preparation	This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.

Specificity

Predicted Reactivity

Mouse

Other Names

COL9A1; Collagen alpha-1(IX) chain

NCBI Accession #

NP_001842.3;NP_511040.2

Other Accession #

Q05722

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

91869

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	COL9A1 Antibody (Center) (Cat# 102-15126) western blot analysis in MCF-7 cell line and mouse eyeball,rat eyeball tissue lysates (35ug/lane).This demonstrates the COL9A1 antibody detected the COL9A1 protein (arrow).
	COL9A1 Antibody (Center) (Cat# 102-15126) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the COL9A1 antibody detected the COL9A1 protein (arrow).
	Western blot analysis of anti-COL9A1 Antibody (Center) (Cat# 102-15126) in 293 cell line lysates (35ug/lane). COL9A1(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with COL9A1 antibody (Center) (Cat# 102-15126), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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