Reacts with most mammalian Type V collagens and has negligible cross-reactivity with Type I, II, III, IV, and VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible. Typically less than 1% cross reactivity against other types of collagen was detected using ELISA against purified standards. Some class specific anti -collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues.

Upon receipt, store at 2-8 °C as an undiluted liquid. Prepare working dilution only prior to immediate use. For long term storage, mix with an equal volume of glycerol, aliquot and store at -20 °C. Avoid multiple freeze/thaw cycles. Expiration date is one (1) year from opening.