RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-COPE (C-term) Antibody

Catalog #: 102-11049

Rabbit Anti-Human COPE (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O14579
Gene Id
11316
Gene Symbols
COPE
Protein Name / Synonyms
COPE (C-term)
ClonalityPolyclonal
PreparationThis COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.
Concentration (lot specific)
0.250 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P, IF
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specificity

Predicted Reactivity
Mouse, Chicken, Hamster
Other Names
COPE; Coatomer subunit epsilon; Epsilon-coat protein
NCBI Accession #
NP_009194.2;NP_955474.1;NP_955476.1
Other Accession #
O89079; Q60445; Q5ZIK9; NP_009194.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
34482
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
COPE Antibody (C-term) (Cat# 102-11049) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the COPE antibody detected the COPE protein (arrow).
COPE Antibody (C-term) (Cat# 102-11049)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COPE Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of COPE Antibody (C-term)(Cat# 102-11049) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.