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Anti-CREB3 (N-term) Antibody

Catalog #: 102-14515

Rabbit Anti-Human CREB3 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O43889
Gene Id
10488
Gene Symbols
CREB3
Protein Name / Synonyms
CREB3 (N-term)
ClonalityPolyclonal
PreparationThis CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.
Concentration (lot specific)
0.380 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Specificity

Other Names
CREB3; LZIP; Cyclic AMP-responsive element-binding protein 3; Leucin zipper proitein; Luman; Transcription factor LZIP-alpha; Processed cyclic AMP-responsive element-binding protein 3
NCBI Accession #
NP_006359.3
Other Accession #
NP_006359.3

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
43917
Recommended Dilutions
WB: 1:1000
CREB3 Antibody (N-term) (Cat# 102-14515) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CREB3 antibody detected the CREB3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.