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Anti-CRIPTO (TDGF1) (N-term) Antibody
Catalog #: 102-14825
Rabbit Anti-Human CRIPTO (TDGF1) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P13385 |
| Gene Id | 6997 |
| Gene Symbols | TDGF1 |
| Protein Name / Synonyms | CRIPTO (TDGF1) (N-term) |
| Clonality | Polyclonal |
| Preparation | This CRIPTO (TDGF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human CRIPTO (TDGF1). |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.
Specificity
Other Names
TDGF1; CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; Epidermal growth factor-like cripto protein CR1
NCBI Accession #
NP_001167607.1;NP_003203.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21169
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of CRIPTO (TDGF1) Antibody (N-term) (Cat# 102-14825) in Jurkat cell line lysates (35ug/lane). TDGF1 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.