Anti-CRTC2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q53ET0
Gene Id	200186
Gene Symbols	CRTC2
Protein Name / Synonyms	CRTC2 (C-term)
Clonality	Polyclonal
Preparation	This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 664-693 amino acids from the C-terminal region of human CRTC2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Specificity

Other Names

CRTC2; TORC2; CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2

NCBI Accession #

NP_859066.1

Other Accession #

NP_859066.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

73302

Recommended Dilutions

WB: 1:1000

CRTC2 Antibody (C-term) (Cat# 102-12346) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the CRTC2 antibody detected the CRTC2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products