Rabbit Anti-Human CRTC2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q53ET0 |
| Gene Id | 200186 |
| Gene Symbols | CRTC2 |
| Protein Name / Synonyms | CRTC2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the N-terminal region of human CRTC2. |
| Concentration (lot specific) | 0.420 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Specificity
Other Names
CRTC2; TORC2; CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2
NCBI Accession #
NP_859066.1
Other Accession #
NP_859066.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
73302
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | CRTC2 Antibody (N-term) (Cat# 102-12429) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CRTC2 antibody detected the CRTC2 protein (arrow). |
 | CRTC2 Antibody (N-term) (Cat# 102-12429)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRTC2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.