Anti-CSHL1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q14406
Gene Id	1444
Gene Symbols	CSHL1
Protein Name / Synonyms	CSHL1 (C-term)
Clonality	Polyclonal
Preparation	This CSHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human CSHL1.
Concentration (lot specific)	0.360 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specificity

Other Names

CSHL1; CSHP1; CSL; Chorionic somatomammotropin hormone-like 1; Lactogen-like

NCBI Accession #

NP_072101.1;NP_072102.1;NP_072103.1

Other Accession #

P01243; NP_072103.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

25391

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of lysate from human placenta tissue lysate, using CSHL1 Antibody (C-term)(Cat# 102-11845). 102-11845 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
	CSHL1 Antibody (C-term) (Cat#AP13044a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSHL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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