Anti-CSNK1A1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P48729
Gene Id	1452
Gene Symbols	CSNK1A1
Protein Name / Synonyms	CSNK1A1 (C-term)
Clonality	Polyclonal
Preparation	This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1.
Concentration (lot specific)	1.300 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.

Specificity

Predicted Reactivity

Chicken, Xenopus

Other Names

CSNK1A1; Casein kinase I isoform alpha; CK1

NCBI Accession #

NP_001020276.1;NP_001258670.1;NP_001258671.1;NP_001883.4

Other Accession #

P67963; P67962

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

38915

Recommended Dilutions

IHC: 1:10-50; WB: 1:1000

	Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CK1a antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Western blot analysis of anti-CK1a Pab (Cat# 102-17325) in A375 cell lysate. CK1a (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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