Anti-CTGF Antibody

Catalog #: DS-PB-02576

Rabbit Anti-Human CTGF

Product Description

Specifications

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product specifically recognizes human CTGF (connective tissue growth factor), a 323 amino acid polypeptide and member of the CCN family of secreted cysteine rich regulatory proteins, which is produced by vascular endothelial and umbilical vein cells, and interacts with several other growth factors, including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs). CTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis. CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and also promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF induces extracellular matrix formation, including the deposition of excessive collagen in fibrotic diseases, and has also been implicated in wound healing.
Host Species	Rabbit
Protein Name / Synonyms	CTGF
Preparation	Antisera to human CTGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Concentration (lot specific)	IgG concentration 1.0mg/ml after reconstitution.
Recommended Applications	ELISA (dilution: 0.1, 0.2ug/ml), Functional Assays, Immunofluorescence, Immunohistology - Paraffin, Western Blotting
Reconstitution	Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB: For functional studies do not add azide.
Shipping Type	Ambient temperature
Storage	-20°C

Description

Storage/Stability

Prior to reconstitution store at +4 °C.
After reconstitution store at -20 °C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:

Purified IgG - lyophilized

Formulation:

Phosphate buffered saline

Reconstitution:

Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB: For functional studies do not add azide.

Format Type:

Purified

Preparation

Antisera to human CTGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Immunogen:

Recombinant human CTGF.

Preservative:

None present

Expiration:

12 months from the date of shipment when stored properly.

Featured Products