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Anti-CTNNB1 (Ascites) Antibody
Catalog #: 102-10305
Mouse Anti-Human CTNNB1 (Ascites) Antibody, 0.1 ml
Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P35222 |
| Gene Id | 1499 |
| Gene Symbols | CTNNB1 |
| Protein Name / Synonyms | CTNNB1 (Ascites) |
| Clonality | Monoclonal |
| Preparation | This CTNNB1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 646-673 amino acids from human CTNNB1. |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer, Wnt-beta-Catenin Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Drosophila, Xenopus
Other Names
CTNNB1; CTNNB; Catenin beta-1; Beta-catenin
NCBI Accession #
NP_001091679.1;NP_001091680.1;NP_001895.1
Other Accession #
P26233; Q9WU82; Q02248; Q0VCX4; P18824; NP_001091679.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
85497
Recommended Dilutions
WB: 1:200-1600
 | CTNNB1 Antibody (Cat# 102-10305) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the CTNNB1 antibody detected the CTNNB1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.