Anti-CTPS2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NRF8
Gene Id	56474
Gene Symbols	CTPS2
Protein Name / Synonyms	CTPS2 (N-term)
Clonality	Polyclonal
Preparation	This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human CTPS2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

CTPS2; CTP synthase 2; CTP synthetase 2; UTP--ammonia ligase 2

NCBI Accession #

NP_001137474.1;NP_062831.3;NP_787055.1

Other Accession #

Q5U2N0; P70303; Q1RMS2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

65678

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of CTPS2 Antibody (N-term) (Cat# 102-18024) in Hela cell line lysates (35ug/lane). CTPS2 (arrow) was detected using the purified Pab.
	CTPS2 Antibody (N-term) (Cat# 102-18024) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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