Rabbit Anti-Human CXCR4(N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P61073 |
| Gene Id | 7852 |
| Gene Symbols | CXCR4 |
| Protein Name / Synonyms | CXCR4(N-term) |
| Clonality | Polyclonal |
| Preparation | This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation, Autoimmune Disease, Chemokine Biology |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig, Monkey
Other Names
CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; NPYRL; Stromal cell-derived factor 1 receptor; CD_antigen=CD184
NCBI Accession #
NP_001008540.1;NP_003458.1
Other Accession #
O08565; Q764M9; P70658; Q28474; P25930; NP_001008540.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39746
Recommended Dilutions
WB: 1:1000
 | CXCR4 Antibody (N-term) (Cat# 102-14302) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CXCR4 antibody detected the CXCR4 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.