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Anti-Cyclin H Antibody
Catalog #: 102-26480
Mouse Anti-Cyclin H Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P51946 |
| Gene Id | 902 |
| Gene Symbols | CCNH |
| Protein Name / Synonyms | 6330408H09Rik;AI661354;AV102684;AW538719;CAK;CAK complex subunit;ccnh;CCNH_HUMAN;CDK activating kinase;CDK activating kinase complex subunit;Cyclin dependent kinase activating kinase;cyclin dependent kinase activating kinase complex subunit;Cyclin |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting, IP |
| Research Area | Cell Cycle |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot detection of Cyclin H in Jurkat,K562 and A431 cell lysates using Cyclin H mouse mAb (1:1000 diluted).Predicted band size: 38KDa.Observed band size: 38KDa.
IP (1:500)
Immunoprecipitation analysis of Hela cell lysates using Cyclin H mouse mAb.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.