Anti-CYP1A1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P04798
Gene Id	1543
Gene Symbols	CYP1A1
Protein Name / Synonyms	CYP1A1 (C-term)
Clonality	Monoclonal
Preparation	This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.
Concentration (lot specific)	0.370 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Specificity

Predicted Reactivity

Monkey

Other Names

CYP1A1; Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1

NCBI Accession #

NP_000490.1

Other Accession #

P33616; NP_000490

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

58165

Recommended Dilutions

WB: 1:100-1000

CYP1A1 Antibody (C-term) (Cat# 102-10388) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CYP1A1 antibody detected the CYP1A1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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