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Anti-CYP1A1 (C-term) Antibody
Catalog #: 102-17742
Rabbit Anti-CYP1A1 (C-term) Antibody, 200 µl
Product Description
Specifications
| Size | 200 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P04798 |
| Gene Id | 1543 |
| Gene Symbols | CYP1A1 |
| Protein Name / Synonyms | CYP1A1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CYP1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.
Specificity
Predicted Reactivity
Monkey
Other Names
CYP1A1; Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1
NCBI Accession #
NP_000490.1
Other Accession #
P33616
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
58165
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-CYP1A1 Antibody (C-term) (Cat# 102-17742) in K562 cell line lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab. |
 | Western blot analysis of anti-CYP1A1 Antibody (C-term) (Cat# 102-17742) in mouse lung tissue lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.