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Anti-CYP1A1 (Center) Antibody
Catalog #: 102-17743
Rabbit Anti-CYP1A1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P04798 |
| Gene Id | 1543 |
| Gene Symbols | CYP1A1 |
| Protein Name / Synonyms | CYP1A1 (Center) |
| Clonality | Polyclonal |
| Preparation | This CYP1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the Central region of human CYP1A1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IF, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.
Specificity
Other Names
CYP1A1; Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1
NCBI Accession #
NP_000490.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
58165
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; IHC: 1:10-50
 | Western blot analysis of anti-CYP1A1 Antibody (Center) (Cat# 102-17743) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab. |
 | Confocal immunofluorescent analysis of CYP1A1 Antibody (Center)(Cat# 102-17743) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
 | CYP1A1 Antibody (Center) (Cat# 102-17743)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP1A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.