Anti-CYP1A2 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P05177
Gene Id	1544
Gene Symbols	CYP1A2
Protein Name / Synonyms	CYP1A2
Clonality	Monoclonal
Preparation	This CYP1A2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from human CYP1A2.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Specificity

Other Names

CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P(3)450; Cytochrome P450 4; Cytochrome P450-P3

NCBI Accession #

NP_000752.2

Other Accession #

NP_000752.2

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

58294

Recommended Dilutions

WB: 1:100-250

CYP1A2 Antibody (Cat# 102-10296) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CYP1A2 antibody detected the CYP1A2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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