Anti-CYP2R1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q6VVX0
Gene Id	120227
Gene Symbols	CYP2R1
Protein Name / Synonyms	CYP2R1 (Center)
Clonality	Polyclonal
Preparation	This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CYP2R1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.

Specificity

Other Names

CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1

NCBI Accession #

NP_078790.2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

57359

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of CYP2R1 Antibody (Center) (Cat# 102-17685) in NCI-H460 cell line(lane 1) and mouse liver tissue(lane 2) lysates (35ug/lane). CYP2R1 (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human brain tissue reacted with CYP2R1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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