Anti-CYTH3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	O43739
Gene Id	9265
Gene Symbols	CYTH3
Protein Name / Synonyms	CYTH3 (C-term)
Clonality	Polyclonal
Preparation	This CYTH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the C-terminal region of human CYTH3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.

Specificity

Predicted Reactivity

Rat

Other Names

CYTH3; ARNO3; GRP1; PSCD3; Cytohesin-3; ARF nucleotide-binding site opener 3; General receptor of phosphoinositides 1; PH, SEC7 and coiled-coil domain-containing protein 3

NCBI Accession #

NP_004218.1

Other Accession #

P97696; O08967

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46349

Recommended Dilutions

WB: 1:1000

	Western blot analysis of CYTH3 Antibody (C-term) (Cat# 102-18350) in Hela cell line lysates (35ug/lane). CYTH3 (arrow) was detected using the purified Pab;
	Western blot analysis of CYTH3 Antibody (C-term) (Cat# 102-18350) in mouse cerebellum tissue lysates (35ug/lane). CYTH3 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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