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Anti-DDR2 (Ascites) Antibody
Catalog #: 102-10283
Mouse Anti-Human DDR2(Ascites) Antibody, 0.1 ml
Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | Q16832 |
| Gene Id | 4921 |
| Gene Symbols | DDR2 |
| Protein Name / Synonyms | DDR2(Ascites) |
| Clonality | Monoclonal |
| Preparation | This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2. |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq].
Specificity
Other Names
DDR2; NTRKR3; TKT; TYRO10; Discoidin domain-containing receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; CD_antigen=CD167b; Flags: Precursor
NCBI Accession #
NP_001014796.1;NP_006173.2
Other Accession #
NP_001014796.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
96736
Recommended Dilutions
WB: 1:100-1600
 | DDR2 Antibody (Cat# 102-10283) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the DDR2 antibody detected the DDR2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.