Anti-DDX11 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96FC9
Gene Id	1663
Gene Symbols	DDX11
Protein Name / Synonyms	DDX11 (C-term)
Clonality	Polyclonal
Preparation	This DDX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 819-847 amino acids from the C-terminal region of human DDX11.
Concentration (lot specific)	0.290 mg/ml
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specificity

Other Names

DDX11; CHL1; CHLR1; KRG2; Probable ATP-dependent RNA helicase DDX11; CHL1-related protein 1; DEAD/H box protein 11; Keratinocyte growth factor-regulated gene 2 protein

NCBI Accession #

NP_001244073.1;NP_001244074.1;NP_004390.3;NP_689651.1

Other Accession #

NP_689651.1; NP_004390.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

108313

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	DDX11 Antibody (C-term) (Cat# 102-11146) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DDX11 antibody detected the DDX11 protein (arrow).
	DDX11 Antibody (C-term) (Cat# 102-11146) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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