Anti-Desmin (T16) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P17661
Gene Id	1674
Gene Symbols	DES
Protein Name / Synonyms	Desmin (T16)
Clonality	Polyclonal
Preparation	This Desmin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human Desmin.
Concentration (lot specific)	0.258 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Desmin is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in the gene encoding desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Pig

Other Names

DES; Desmin

NCBI Accession #

NP_001918.3

Other Accession #

P48675; P02540; P31001; O62654

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

53536

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-Desmin Antibody (t16) (Cat# 102-15119) in NCI-H460 cell line lysates (35ug/lane).Desmin-pT16(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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