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Anti-DIO1 (N-term) Antibody
Catalog #: 102-17037
Rabbit Anti-Human DIO1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49895 |
| Gene Id | 1733 |
| Gene Symbols | DIO1 |
| Protein Name / Synonyms | DIO1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1. |
| Concentration (lot specific) | 0.315 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).
Specificity
Other Names
DIO1; ITDI1; TXDI1; Type I iodothyronine deiodinase; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase
NCBI Accession #
NP_000783.2;NP_001034804.1;NP_001034805.1;NP_998758.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
28924
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of DIO1 Antibody (N-term) (Cat# 102-17037) in HepG2 cell line lysates (35ug/lane). DIO1 (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.