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Anti-Diphtheria Toxin
Catalog #: 131-0226
Mouse Anti-Bacteria Diphtheria Toxin Monoclonal Antibody (Clone: 5D1-B1-F3-H2, 4B5-C9-H10-H8, 4D1-B5-H2-G4, and 5C10-A10-H12-G9)
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg, 1 mg |
| Estimated Lead Time | 1-2 business days |
| Species | Bacteria |
| Host Species | Mouse |
| Accession Number | P00588 |
| Protein Name / Synonyms | Diphtheria toxin (DT); NAD(+)--diphthamide ADP-ribosyltransferase |
| Clonality | Monoclonal |
| Clone | 5D1-B1-F3-H2, 4B5-C9-H10-H8, 4D1-B5-H2-G4, 5C10-A10-H12-G9 |
| Preparation | The antibody was generated from a hybridoma produced by fusing a mouse myeloma cell line with B cells isolated from a mouse immunized with the immunogen. The IgG fraction was purified from tissue culture supernatant using Protein G/A affinity chromatography. |
| Immunogen | The immunogen was the Diphtheria Toxin CRM197 mutant. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1:32, 000) |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in glycine solution. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Description
Diphtheria toxin is an exotoxin produced by Corynebacterium diphtheriae. It inhibits protein synthesis by disrupting the peptide chain release factor (EF-2) of host cells, ultimately leading to cell death. Due to its specific killing mechanism, it is widely used in tumor treatment and immunological research.
Storage/Stability
Store at -20°C. If intended for use within a month, may keep at 4°C. Minimize freeze-thaw cycles.
Expiration
12 months from the date of shipment when stored properly.