Anti-DNMT3A (C-term V897) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y6K1
Gene Id	1788
Gene Symbols	DNMT3A
Protein Name / Synonyms	DNMT3A (C-term V897)
Clonality	Polyclonal
Preparation	This DNMT3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 872-900 amino acids from the C-terminal region of human DNMT3A.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Specificity

Predicted Reactivity

Mouse, Rat, Chicken

Other Names

DNMT3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase HsaIIIA

NCBI Accession #

NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1

Other Accession #

Q1LZ53; O88508; Q4W5Z4; NP_783328.1; NP_715640.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

101858

Recommended Dilutions

WB: 1:1000

DNMT3A Antibody (C-term V897) (Cat# 102-12916) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DNMT3A antibody detected the DNMT3A protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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