Anti-Dnmt3A/Dnmt3A2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y6K1
Gene Id	1788
Gene Symbols	DNMT3A
Protein Name / Synonyms	Dnmt3A/Dnmt3A2 (C-term)
Clonality	Polyclonal
Preparation	This Dnmt3A/Dnmt3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the C-terminal region of human Dnmt3A/Dnmt3A2.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

DNMT3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase HsaIIIA

NCBI Accession #

NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1

Other Accession #

Q1LZ53; O88508

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

101858

Recommended Dilutions

WB: 1:1000

Western blot analysis of DNMT3A Antibody (C-term) (Cat# 102-10604) in HepG2 cell line lysates (35ug/lane). DNMT3A (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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