Anti-DPEP1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P16444
Gene Id	1800
Gene Symbols	DPEP1
Protein Name / Synonyms	DPEP1(N-term)
Clonality	Polyclonal
Preparation	This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).

Specificity

Other Names

DPEP1; MDP; RDP; Dipeptidase 1; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase

NCBI Accession #

NP_001121613.1;NP_004404.1

Other Accession #

NP_001121613.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

45674

Recommended Dilutions

WB: 1:1000

DPEP1 Antibody (N-term) (Cat# 102-14371) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DPEP1 antibody detected the DPEP1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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