Anti-DPYSL2 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q16555
Gene Id	1808
Gene Symbols	DPYSL2
Protein Name / Synonyms	DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2, dihydropyrimidinase like 2
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW

58kDa/62kDa

Observed MW

69kDa

Immunogen

A phospho specific peptide corresponding to residues surrounding T514 of human DPYSL2

Modification

Phospho T514

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using Phospho-DPYSL2-T514 antibody (144-61537) at 1:1000 dilution or DPYSL2 antibody (144-60712). SH-SY5Y cells were treated by CIP(20uL/400ul) at 37? for 1 hour. PC-12 cells were treated by CIP(20uL/400ul) at 37? for 1 hour.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit.
Exposure time: 1s.
Western blot - Phospho-DPYSL2-T514 pAb (144-61537)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products