RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-DR5 Antibody

Catalog #: 102-26546

Mouse Anti-DR5 Antibody, 100 µl

Product Description

Specifications

Size100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesMouse
Accession Number
O14763
Gene Id
8795
Gene Symbols
TNFRSF10B
Protein Name / Synonyms
Fas like protein ;Apoptosis inducing protein TRICK2A/2B ;Apoptosis inducing receptor TRAIL R2 ;CD 262 ;CD262 ;CD262 antigen ;Cytotoxic TRAIL receptor 2 ;Death domain containing receptor for TRAIL/Apo 2L ;Death domain containing receptor for TRAIL/Apo2L ;Death receptor 5 ;DR 5 ;DR5 ;Fas like protein precursor ;KILLER ;KILLER/DR5 ;OTTHUMP00000123492 ;OTTHUMP00000123493 ;p53 regulated DNA damage inducible cell death receptor (killer) ;p53 regulated DNA damage inducible cell death receptor(killer) ;TNF related apoptosis inducing ligand receptor 2 ;TNF related apoptosis inducing ligand receptor 2 ;TNF-related apoptosis-inducing ligand receptor 2 ;TNFRSF10B ;TR10B_HUMAN ;TRAIL R2 ;TRAIL receptor 2 ;TRAIL-R2 ;TRAILR2 ;TRANCER ;TRICK2 ;TRICK2A ;TRICK2B ;TRICKB ;Tumor necrosis factor receptor like protein ZTNFR9 ;Tumor necrosis factor receptor like protein ZTNFR9 ;Tumor necrosis factor receptor superfamily member 10b ;Tumor necrosis factor receptor superfamily, member 10b ;ZTNFR9
ClonalityMonoclonal
Recommended ApplicationsWestern Blotting
Research AreaCancer
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis.

Other Information

Antigen Type
Recombinant Protein

Images

WB (1:1000)

Western blot detection of DR5 in SW480,K562,HCT116 and Hela cell lysates using DR5 mouse mAb (1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.