Anti-DRAK2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	O94768
Gene Id	9262
Gene Symbols	STK17B
Protein Name / Synonyms	DRAK2 (C-term)
Clonality	Polyclonal
Preparation	This DRAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human DRAK2.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DRAK2 is a novel serine/threonine kinase that induces apoptosis via catalytic activity. DRAKs present high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases. DRAK2 is located in nucleus, and the messenger RNA is ubiquitously expressed in human tissues.

Specificity

Other Names

STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2

NCBI Accession #

NP_004217.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

42344

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100; IF: 1:10-50

	The anti-DRAK2 Pab (Cat# 102-17192) is used in Western blot to detect DRAK2 in mouse lung tissue lysate.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
	IF staining of Drak2 in WT versus Tg T cells. Permeablized lymph node T cells were double-stained with rabbit anti-Drak2/sheep anti-rabbit Ig-FITC and anti-Thy1.2-PE monoclonal antibody, and signals were registered by confocal microscopy. THE cell surface Thy1.2 is shown in red, and intracellular Drak2 is in green.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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