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Anti-DRAP1 (N-term) Antibody
Catalog #: 102-13729
Rabbit Anti-Human DRAP1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q14919 |
| Gene Id | 10589 |
| Gene Symbols | DRAP1 |
| Protein Name / Synonyms | DRAP1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This DRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human DRAP1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
DRAP1; Dr1-associated corepressor; Dr1-associated protein 1; Negative co-factor 2-alpha
NCBI Accession #
NP_006433.2
Other Accession #
A0JPP1; Q9D6N5; Q2YDP3; NP_006433.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22350
Recommended Dilutions
WB: 1:1000
 | DRAP1 Antibody (N-term) (Cat# 102-13729) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the DRAP1 antibody detected the DRAP1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.