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Anti-Dsk2 (N-term) Antibody
Catalog #: 102-15005
Rabbit Anti-Human Dsk2 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UHD9 |
| Gene Id | 29978 |
| Gene Symbols | UBQLN2 |
| Protein Name / Synonyms | Dsk2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This Dsk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human Dsk2. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
UBQLN2; N4BP4; PLIC2; Ubiquilin-2; Chap1; DSK2 homolog; Protein linking IAP with cytoskeleton 2; Ubiquitin-like product Chap1/Dsk2
NCBI Accession #
NP_038472.2
Other Accession #
Q9QZM0; Q9JJP9; Q8R317; Q9UMX0
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
65696
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-Dsk2 Pab (Cat# 102-15005) is used in Western blot to detect Dsk2 in HeLa cell lysate. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Dsk2 Antibody (N-term) (Cat# 102-15005), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.