Anti-DSP Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P15924
Gene Id	1832
Gene Symbols	DSP
Protein Name / Synonyms	DSP, DCWHKTA, DP, desmoplakin
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW

260kDa/278kDa/331kDa

Observed MW

315kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 2750-2850 of human DSP (NP_004406.2).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of HepG2 cells, using DSP antibody (144-60272) at 1:800 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 60s.
Western blot - DSP Polyclonal Antibody (144-60272)

Immunohistochemistry of paraffin-embedded human gastric cancer using DSP antibody (144-60272) at dilution of 1:100 (40x lens).
Immunohistochemistry - DSP Polyclonal Antibody (144-60272)

Immunohistochemistry of paraffin-embedded mouse heart using DSP antibody (144-60272) at dilution of 1:100 (40x lens).
Immunohistochemistry - DSP Polyclonal Antibody (144-60272)

Expiration:

12 months from the date of shipment when stored properly.

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