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Anti-DTNA Antibody
Catalog #: 144-62192
DTNA pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9Y4J8 |
| Gene Id | 1837 |
| Gene Symbols | DTNA |
| Protein Name / Synonyms | DTNA, D18S892E, DRP3, DTN, DTN-A, LVNC1, dystrobrevin alpha |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
22kDa/36kDa/41-44kDa/50kDa/58-83kDa
Observed MW
84kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 240-480 of human DTNA (NP_001381.2).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.