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Anti-DTYMK (C-term) Antibody
Catalog #: 102-27149
Rabbit Anti-DTYMK (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P23919 |
| Gene Id | 1841 |
| Gene Symbols | DTYMK |
| Protein Name / Synonyms | Thymidylate kinase, dTMP kinase, DTYMK, CDC8, TMPK, TYMK |
| Clonality | Polyclonal |
| Clone | RB5576 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
Other Information
NCBI Accession #
NP_036277.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
23819
Antigen Source
Human
Images
WB (1:1000)
The anti-DTYMK Pab (Cat. #102-27149) is used in Western blot to detect DTYMK in mouse colon tissue lysate.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.