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Anti-DUSP7 (N-term) Antibody
Catalog #: 102-17880
Rabbit Anti-Human DUSP7 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16829 |
| Gene Id | 1849 |
| Gene Symbols | DUSP7 |
| Protein Name / Synonyms | DUSP7 (N-term) |
| Clonality | Polyclonal |
| Preparation | This DUSP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-127 amino acids from the N-terminal region of human DUSP7. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Specificity
Predicted Reactivity
Mouse
Other Names
DUSP7; PYST2; Dual specificity protein phosphatase 7; Dual specificity protein phosphatase PYST2
NCBI Accession #
NP_001938.2
Other Accession #
Q91Z46; NP_001938
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44957
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of DUSP7 (arrow) using DUSP7 Antibody (N-term) (RB05816). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP7 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.