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Anti-E2F3 (Center) Antibody
Catalog #: 102-12564
Rabbit Anti-Human E2F3 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O00716 |
| Gene Id | 1871 |
| Gene Symbols | E2F3 |
| Protein Name / Synonyms | E2F3 (Center) |
| Clonality | Polyclonal |
| Preparation | This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Specificity
Predicted Reactivity
Mouse
Other Names
E2F3; KIAA0075; Transcription factor E2F3
NCBI Accession #
NP_001230005.1;NP_001940.1
Other Accession #
O35261; NP_001940.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49162
Recommended Dilutions
WB: 1:1000
 | E2F3 Antibody (Center) (Cat# 102-12564) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the E2F3 antibody detected the E2F3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.