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Anti-EBV LMP2A Antibody
Catalog #: DS-MB-03627
Rat Anti-EBV LMP2A
Product Description
Specifications
| Size | 0.25 mg |
| Estimated Lead Time | 1-2 weeks |
| Specificity | This product recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin❏'s disease and Burkitt❏'s Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. This product specifically recognizes LMP2A and does not cross react with LMP2B. |
| Protein Name / Synonyms | EBV LMP2A |
| Concentration (lot specific) | IgG concentration 1.0 mg/ml |
| Recommended Applications | Immunohistology - Paraffin, Western Blotting |
| Research Area | Apoptosis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Bacterial TrpE-LMP2A fusion protein
Preservative:
0.09% Sodium Azide
This product
Spleen cells from immunised Lou/c rats were fused with cells of the P3X63.Ag8.653 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.