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Anti-EDN3 (C-term) Antibody
Catalog #: 102-10995
Rabbit Anti-Human EDN3 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P14138 |
| Gene Id | 1908 |
| Gene Symbols | EDN3 |
| Protein Name / Synonyms | EDN3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This EDN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human EDN3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Specificity
Other Names
EDN3; Endothelin-3; Preproendothelin-3
NCBI Accession #
NP_000105.1;NP_996915.1;NP_996916.1;NP_996917.1
Other Accession #
Q03229; NP_000105
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
25454
Recommended Dilutions
WB: 1:1000
 | EDN3 Antibody (C-term) (Cat# 102-10995) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the EDN3 antibody detected the EDN3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.