Anti-EHMT1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9H9B1
Gene Id	79813
Gene Symbols	EHMT1
Protein Name / Synonyms	EHMT1 (C-term)
Clonality	Polyclonal
Preparation	This EHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1174 amino acids from the C-terminal region of human EHMT1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

Specificity

Predicted Reactivity

Mouse

Other Names

EHMT1; EUHMTASE1; GLP; KIAA1876; KMT1D; Histone-lysine N-methyltransferase EHMT1; Euchromatic histone-lysine N-methyltransferase 1; G9a-like protein 1; Histone H3-K9 methyltransferase 5; Lysine N-methyltransferase 1D

NCBI Accession #

NP_001138999.1;NP_079033.4

Other Accession #

Q5DW34

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

141466

Recommended Dilutions

WB: 1:1000

Western blot analysis of EHMT1 (arrow) using rabbit polyclonal EHMT1 Antibody (C-term) (Cat# 102-10587). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EHMT1 gene (Lane 2) (Origene Technologies).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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