Anti-ELAVL3 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q14576
Gene Id	1995
Gene Symbols	ELAVL3
Protein Name / Synonyms	ELAVL3 (N-term)
Clonality	Polyclonal
Preparation	This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specificity

Predicted Reactivity

Mouse

Other Names

ELAVL3; HUC; PLE21; ELAV-like protein 3; Hu-antigen C; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic limbic encephalitis antigen 21

NCBI Accession #

NP_001411.2;NP_115657.2

Other Accession #

Q60900; NP_115657.2; NP_001411.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39547

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term)(Cat# 102-11971). 102-11971 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
	Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody (N-term)(Cat# 102-11971). 102-11971 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
	ELAVL3 Antibody (N-term) (Cat# 102-11971)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELAVL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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