3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-Elongin A (N-term) Antibody
Catalog #: 102-14175
Rabbit Anti-Elongin A (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q14241 |
| Gene Id | 6924 |
| Gene Symbols | TCEB3 |
| Protein Name / Synonyms | Elongin A (N-term) |
| Clonality | Polyclonal |
| Preparation | This Elongin A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-127 amino acids from the N-terminal region of human Elongin A. |
| Concentration (lot specific) | 0.310 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Elongin A is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Specificity
Other Names
TCEB3; Transcription elongation factor B polypeptide 3; Elongin 110 kDa subunit; Elongin-A; RNA polymerase II transcription factor SIII subunit A1; SIII p110
NCBI Accession #
NP_003189.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
89909
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of Elongin A (arrow) using rabbit polyclonal Elongin A Antibody (Cat# 102-14175). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Elongin A gene. |
 | Elongin A Antibody (Cat# 102-14175) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Elongin A antibody detected the Elongin A protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.