Endoglin. also known as CD105, is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. Beside TGF-beta signaling, endoglin has other functions, such as affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development.

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat Endoglin has not yet been tested.

Human Endoglin ELISA Kit (Cat# ELH-Endoglin-001 )Rabbit Anti-Endoglin antibody-C-terminus(Cat# 130-10021)Recombinant Human Endoglin (Cat# 228-10387)