3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-ENG (Center) Antibody
Catalog #: 102-11006
Rabbit Anti-Human ENG (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P17813 |
| Gene Id | 2022 |
| Gene Symbols | ENG |
| Protein Name / Synonyms | ENG (Center) |
| Clonality | Polyclonal |
| Preparation | This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG. |
| Concentration (lot specific) | 0.300 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Angiogenesis, Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
ENG; END; Endoglin; CD_antigen=CD105; Flags: Precursor
NCBI Accession #
NP_000109.1;NP_001108225.1;NP_001265067.1
Other Accession #
NP_001108225.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
70578
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of ENG (arrow) using rabbit polyclonal ENG Antibody (Center) (Cat# 102-11006). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ENG gene. |
 | ENG Antibody (Center) (Cat# 102-11006) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.