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Anti-ENPP2 (Center) Antibody
Catalog #: 102-15184
Rabbit Anti-ENPP2 (Center) Antibody, 200 µl
Product Description
Specifications
| Size | 200 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q13822 |
| Gene Id | 5168 |
| Gene Symbols | ENPP2 |
| Protein Name / Synonyms | ENPP2 (Center) |
| Clonality | Polyclonal |
| Preparation | This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the Central region of human ENPP2. |
| Concentration (lot specific) | 0.4 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.
Specificity
Other Names
ENPP2; ATX; PDNP2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Autotaxin; Extracellular lysophospholipase D
NCBI Accession #
NP_001035181.1;NP_001124335.1;NP_006200.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
98994
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of ENPP2 (arrow) using rabbit polyclonal ENPP2 Antibody (Center) (Cat# 102-15184). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ENPP2 gene (Lane 2) (Origene Technologies). |
 | Western blot analysis of ENPP2 Antibody (Center) (Cat# 102-15184) in mouse cerebellum tissue lysates (35ug/lane). ENPP2 (arrow) was detected using the purified Pab. |
 | ENPP2 Antibody (Center) (Cat# 102-15184) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.