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Anti-ENPP2 (Center K416) Antibody
Catalog #: 102-15183
Rabbit Anti-Human ENPP2 (Center K416) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13822 |
| Gene Id | 5168 |
| Gene Symbols | ENPP2 |
| Protein Name / Synonyms | ENPP2 (Center K416) |
| Clonality | Polyclonal |
| Preparation | This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human ENPP2. |
| Concentration (lot specific) | 2.000 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. This protein is secreted and further processed to make the biologically active form.
Specificity
Predicted Reactivity
Bovine
Other Names
ENPP2; ATX; PDNP2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Autotaxin; Extracellular lysophospholipase D
NCBI Accession #
NP_001035181.1;NP_001124335.1;NP_006200.3
Other Accession #
A1A4K5
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
98994
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of anti-ENPP2 Antibody (Center K416) (Cat# 102-15183) in Y79 cell line lysates (35ug/lane).ENPP2(arrow) was detected using the purified Pab. |
 | Western blot analysis of anti-ENPP2 Antibody (Center K416) (Cat# 102-15183) in mouse cerebellum tissue lysates (35ug/lane).ENPP2(arrow) was detected using the purified Pab. |
 | ENPP2 Antibody (Center K416) (Cat# 102-15183)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ENPP2 Antibody (Center K416) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | ENPP2 Antibody (Center K416) (Cat# 102-15183) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.