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Anti-ENSA (Center) Antibody
Catalog #: 102-10657
Rabbit Anti-ENSA (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O43768 |
| Gene Id | 2029 |
| Gene Symbols | ENSA |
| Protein Name / Synonyms | ENSA (Center) |
| Clonality | Polyclonal |
| Preparation | This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.
Specificity
Predicted Reactivity
Rat, Zebrafish, Bovine, Chicken, Pig, Xenopus
Other Names
ENSA; Alpha-endosulfine; ARPP-19e
NCBI Accession #
NP_004427.1;NP_996925.1;NP_996926.1;NP_996927.1;NP_996928.1;NP_996929.1;NP_996930.1;NP_997051.1
Other Accession #
Q7ZXH9; P60841; P68211; P60840; Q1L8X2; Q5ZIF8; P68210; NP_996927.1; NP_996929.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
13389
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | ENSA Antibody (Center) (Cat# 102-10657) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ENSA antibody detected the ENSA protein (arrow). |
 | ENSA Antibody (Center) (Cat# 102-10657) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the ENSA antibody detected the ENSA protein (arrow). |
 | ENSA Antibody (Center) (Cat# 102-10657) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.