Anti-EPC1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9H2F5
Gene Id	80314
Gene Symbols	EPC1
Protein Name / Synonyms	EPC1 (Center)
Clonality	Polyclonal
Preparation	This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Specificity

Other Names

EPC1;Enhancer of polycomb homolog 1

NCBI Accession #

NP_001258933.1;NP_001258948.1;NP_001269320.1;NP_079485.1

Other Accession #

Q8C9X6

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

93463

Recommended Dilutions

WB: 1:1000

EPC1 Antibody (Center) (Cat# 102-14842) western blot analysis in A2058,Hela cell line and mouse heart tissue lysates (35ug/lane).This demonstrates the EPC1 antibody detected the EPC1 protein (arrow).

Antigen Source

Human

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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