Anti-EphB1 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P54762
Gene Id	2047
Gene Symbols	EPHB1
Protein Name / Synonyms	EphB1
Clonality	Polyclonal
Preparation	This EphB1 antibody is generated from rabbits immunized with a his tag recombinant protein of human EphB1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Specificity

Other Names

EPHB1; ELK; EPHT2; HEK6; NET; Ephrin type-B receptor 1; EPH tyrosine kinase 2; EPH-like kinase 6; Neuronally-expressed EPH-related tyrosine kinase; Tyrosine-protein kinase receptor EPH-2

NCBI Accession #

NP_004432.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

109885

Recommended Dilutions

WB: 1:1000

Western blot analysis of EphB1 (arrow) using rabbit polyclonal EphB1 Antibody (Cat# 102-17471) 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EphB1 gene (Lane 2) (Origene Technologies).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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